Everolimus - is an inhibitor of protein kinase, has antitumor properties. The drug is approved for the treatment of advanced and / or metastatic renal cell carcinoma, if anti-angiogenic therapy is ineffective.
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Everolimus - is an inhibitor of protein kinase, has antitumor properties. The drug is approved for the treatment of advanced and / or metastatic renal cell carcinoma, if anti-angiogenic therapy is ineffective. In the course of research, it was possible to establish that in patients with this disease, which progressed after previous treatment with the use of inhibitors of tyrosine kinases and / or cytokines, Everolimus helped reduce the risk of disease progression and mortality by 67%. The overall survival without the progression of the disease was 4.9 months. In 36% of respondents who took Everolimus , progression of the disease was not observed for 6 months. Also, everolimus significantly improves the quality of life of patients.
Inside Reception should be carried out 1 time per day, every day, preferably at the same time (preferably in the morning) on an empty stomach, or after a small amount of food without fat, drinking a glass of water. Tablets should not be crushed, chewed or crushed.
The duration of therapy is determined by the presence of a clinical effect.
The recommended dose is 10 mg / day. If, during therapy, severe or hardly tolerable side effects develop, the dose may be halved - to 5 mg / day, or the treatment may be suspended.
If Everolimus is used in combination with moderate inhibitors of CYP3A4 and P-HP, the dose of the drug should be reduced to 5 mg / day. In the presence of severe or difficult to tolerate side effects, 5 mg is taken every 2 days.
Dose adjustment is not made in elderly patients (over 65 years) in violation of renal function.
In patients with moderately impaired liver function, the recommended dose is 5 mg / day.
Treatment with Everolimus should be carried out by a doctor with experience with anticancer drugs.
Patients should be informed that during treatment with this drug, as well as during 2 months after the end of therapy, reliable methods of contraception should be used. Buy Everolimus directly from India without intermediation. Price Everolimus from the manufacturer!
During treatment, renal function should be monitored.
Patients who have fungal infections should receive appropriate treatment.
During therapy should not be used means for rinsing the mouth, which contain alcohol, it may contribute to the expression of the oral mucosa.
Regularly during treatment with Everolimus , it is necessary to control the level of glucose in the blood serum. Buy Everolimus Price Everolimus India